中文 
别名:Transcription factor E2F3, E2F-3, E2F3, KIAA0075应用:WB
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. |
| Specification | |
|---|---|
| Aliases | Transcription factor E2F3, E2F-3, E2F3, KIAA0075 |
| Entrez GeneID | 1871 |
| Swissprot | O00716 |
| WB Predicted band size | 49.2kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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Anti-E2F3 Antibody (Center) at 1:1000 dilution + mouse brain lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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E2F3 Antibody (Center) (Cat. #P33988) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the E2F3 antibody detected the E2F3 protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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