别名:EDEM应用:IHC
反应种属:Human, Mouse
规格:50μl/100μl
Description |
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Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2. |
Specification | |
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Aliases | EDEM |
Swissprot | Q92611 |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human EDEM1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
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IHC | 1/10-1/50 |
ELISA | 1/5000-1/10000 |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06410(EDEM1 Antibody) at dilution 1/20. (Original magnification: ×200) | |
The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P06410(EDEM1 Antibody) at dilution 1/20. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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