Rabbit Polyclonal Antibody to EDEM1

包装: 1G|100G|500G|1KG|100KG

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别名:EDEM
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

Description

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

Specification
Aliases	EDEM
Swissprot	Q92611
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human EDEM1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/10-1/50
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06410(EDEM1 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P06410(EDEM1 Antibody) at dilution 1/20. (Original magnification: ×200)