别名:EGF-containing fibulin-like extracellular matrix protein 2; FBLN4;应用:WB,IHC,ICC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene.Giltay R., Matrix Biol. 18:469-480(1999).Zemel R., Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.Katsanis N., Hum. Genet. 106:66-72(2000). |
Specification | |
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Aliases | EGF-containing fibulin-like extracellular matrix protein 2; FBLN4; |
Entrez GeneID | 30008; |
Swissprot | O95967 |
WB Predicted band size | 50kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human EFEMP2. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
ICC | 1/100-1/500 |
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Western blot analysis of extracts from K562 cells and 3T3 cells, using EFEMP2 antibody P42398. |
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Immunofluorescence analysis of A549 cells, using EFEMP2 antibody P42398. |
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Immunohistochemistry analysis of paraffin-embedded human placenta tissue using EFEMP2 antibody P42398. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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