Rabbit Polyclonal Antibody to EFHD2

包装: 1G|100G|500G|1KG|100KG

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别名:SWS1
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
EFHD2 is a calcium-binding adaptor protein associated with pathologically aggregated tau in Alzheimer disease brain and in a mouse model of frontotemporal dementia. EFHD2 has cell type-specific functions, including modulation of intracellular calcium responses, actin dynamics, and microtubule transport. May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

Description

EFHD2 is a calcium-binding adaptor protein associated with pathologically aggregated tau in Alzheimer disease brain and in a mouse model of frontotemporal dementia. EFHD2 has cell type-specific functions, including modulation of intracellular calcium responses, actin dynamics, and microtubule transport. May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

Specification
Aliases	SWS1
Swissprot	Q96C19
WB Predicted band size	27 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human EFHD2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
ELISA	1/5000-1/10000

Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: A549 cell lysate, Primary antibody: P06416(EFHD2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。

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