别名:TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5′-CGCCCCCGC-3′(EGR-site). |
| Specification | |
|---|---|
| Aliases | TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268 |
| Swissprot | P18146 |
| WB Predicted band size | 58 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human EGR1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| ELISA | 1/1000-1/5000 |
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Gel: 8%SDS-PAGE, Lysate: 50 μg, Lane 1-2: RAW264.7, NIH/3T3 cells, Primary antibody: P00348(EGR1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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