库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to EIF2AK3

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别名:PEK; WRS; PERK
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Specification
Aliases PEK; WRS; PERK
Swissprot Q9NZJ5
WB Predicted band size 125 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human EIF2AK3
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/500-1/2000
ELISA 1/5000-1/10000

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P13852(EIF2AK3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。