Rabbit Polyclonal Antibody to EIF2B3

包装: 1G|100G|500G|1KG|100KG

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别名:Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3
应用:WB
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene is one of the subunits of
initiation factor eIF2B, which catalyzes the exchange of eukaryotic
initiation factor 2-bound GDP for GTP. It has also been found to
function as a cofactor of hepatitis C virus internal ribosome entry
site-mediated translation. Mutations in this gene have been
associated with leukodystrophy with vanishing white matter.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.

Specification
Aliases	Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3
Entrez GeneID	8891
Swissprot	Q9NR50
WB Predicted band size	50.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This EIF2B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-441 amino acids from the C-terminal region of human EIF2B3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.