中文 
别名:eIF-3 zeta; eIF3 p66; eIF3d; EIF3S7; Eukaryotic translation initiation factor 3 subunit 7应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. HAMAP-Rule MF_03003Asano K., J. Biol. Chem. 272:27042-27052(1997).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004). |
| Specification | |
|---|---|
| Aliases | eIF-3 zeta; eIF3 p66; eIF3d; EIF3S7; Eukaryotic translation initiation factor 3 subunit 7 |
| Entrez GeneID | 8664; |
| Swissprot | O15371 |
| WB Predicted band size | 64kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human EIF3D. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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Western blot analysis of extracts from 3T3 cells, using EIF3D antibody P42404. |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using EIF3D antibody P42404. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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