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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to EIF4G2

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别名:P97, AAG1, DAP5, NAT1
应用:WB
反应种属:Human, Mouse
规格:50μl/100μl

Description
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Specification
Aliases P97, AAG1, DAP5, NAT1
Swissprot P78344
WB Predicted band size 103 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human EIF4G2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/500-1/2000
ELISA 1/2000-1/5000

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, HepG2 cells, Primary antibody: P03871(EIF4G2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。