Rabbit Polyclonal Antibody to ELAVL3

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别名:HUC; HUCL; PLE21
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Description

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specification
Aliases	HUC; HUCL; PLE21
Swissprot	Q14576
WB Predicted band size	40 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human ELAVL3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/25-1/100
ELISA	1/1000-1/2000

	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P11884(ELAVL3 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P11884(ELAVL3 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11884(ELAVL3 Antibody) at dilution 1/20. (Original magnification: ×200)