中文 
别名:E74-like factor 4; E74-like factor 4 (ets domain transcription factor); ELFR; ETS-related transcription factor Elf-4; Mef应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Transcriptional activator that binds to DNA sequences containing the consensus 5′-WGGA-3′. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter By similarity. Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 By similarity. Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. UniProtKB Q9Z2U4Miyazaki Y., Oncogene 13:1721-1729(1996).Aryee D.N.T., Gene 210:71-78(1998).Ross M.T., Nature 434:325-337(2005). |
| Specification | |
|---|---|
| Aliases | E74-like factor 4; E74-like factor 4 (ets domain transcription factor); ELFR; ETS-related transcription factor Elf-4; Mef |
| Entrez GeneID | 2000; |
| Swissprot | Q99607 |
| WB Predicted band size | 70kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human ELF4. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
 |
Western blot analysis of extracts from Jurkat cells, using ELF4 antibody P42694. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
发表回复