中文 
别名:E41P; EPB4.1; band 4.1; P4.1;应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. ‘Rh-unlinked’ forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986)Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988)Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988) |
| Specification | |
|---|---|
| Aliases | E41P; EPB4.1; band 4.1; P4.1; |
| Entrez GeneID | 2035; |
| Swissprot | P11171 |
| WB Predicted band size | 60kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HepG2 cells treated with PMA using EPB41 (Phospho-Tyr660/418) Antibody P40499.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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