别名:erythropoietin receptor, EPO-R应用:WB
反应种属:Human,Rat
规格:50μl/100μl
Description |
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This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. |
Specification | |
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Aliases | erythropoietin receptor, EPO-R |
Entrez GeneID | 2057; |
Swissprot | P19235 |
WB Predicted band size | 55kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | Synthetic peptide corresponding to a region derived from 31-45 amino acids of Human erythropoietin receptor |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/1000-1/5000 |
ELISA | 1:1000-1:5000 |
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Gel: 10%SDS-PAGE Lane1: 231 cell lysateLane2: 293T cell lysateLane3: Hela cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG – H&L (HRP) at 1/10000 dilutionExposure time: 10 seconds |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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