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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to EPOR

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别名:erythropoietin receptor, EPO-R
应用:WB
反应种属:Human,Rat
规格:50μl/100μl

Description
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Specification
Aliases erythropoietin receptor, EPO-R
Entrez GeneID 2057;
Swissprot P19235
WB Predicted band size 55kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen Synthetic peptide corresponding to a region derived from 31-45 amino acids of Human erythropoietin receptor
Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Application
WB 1/1000-1/5000
ELISA 1:1000-1:5000

Gel: 10%SDS-PAGE Lane1: 231 cell lysateLane2: 293T cell lysateLane3: Hela cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG – H&L (HRP) at 1/10000 dilutionExposure time: 10 seconds

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。