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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to ESX1 (N-term)

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别名:Homeobox protein ESX1, Extraembryonic, spermatogenesis, homeobox 1, Homeobox protein ESX1-N, Homeobox protein ESX1-C, ESX1, ESX1L, ESX1R
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a dual-function 65 kDa protein that
undergoes proteolytic cleavage to produce a 45 kDa N-terminal
fragment with a paired-like homeodomain and a 20 kDa C-terminal
fragment with a proline-rich domain. The C-terminal fragment
localizes to the cytoplasm while the N-terminal fragment localizes
exclusively to the nucleus. In contrast to human, the mouse homolog
has a novel PN/PF motif in the C-terminus and is paternally
imprinted in placental tissue. This gene likely plays a role in
placental development and spermatogenesis.
Specification
Aliases Homeobox protein ESX1, Extraembryonic, spermatogenesis, homeobox 1, Homeobox protein ESX1-N, Homeobox protein ESX1-C, ESX1, ESX1L, ESX1R
Entrez GeneID 80712
Swissprot Q8N693
WB Predicted band size 44.3kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This ESX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human ESX1.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

All lanes : Anti-ESX1 Antibody (N-term) at 1:1000-1:2000 dilution
Lane 1: human ovary lysate
Lane 2: human placenta lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 44 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

ESX1 Antibody (N-term) (Cat. #P33996) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ESX1 antibody detected the ESX1 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。