中文 
别名:BMX; BMX NON-receptor tyrosine kinase; Bone marrow kinase BMX; Epithelial and endothelial tyrosine kinase; NTK38应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.Zhang R, et al. (2003) J Biol Chem 278, 51267-76 Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54 |
| Specification | |
|---|---|
| Aliases | BMX; BMX NON-receptor tyrosine kinase; Bone marrow kinase BMX; Epithelial and endothelial tyrosine kinase; NTK38 |
| Entrez GeneID | 660; |
| Swissprot | P51813 |
| WB Predicted band size | 78kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y(p)-V-S) derived from Human ETK. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) antibody P40590.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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