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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Ezrin (Ab-478)

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别名:Cytovillin; EZRI; p81; VIL2; Villin 2
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.Gould K.L., EMBO J. 8:4133-4142(1989).Turunen O., J. Biol. Chem. 264:16727-16732(1989).Mungall A.J., Nature 425:805-811(2003).
Specification
Aliases Cytovillin; EZRI; p81; VIL2; Villin 2
Entrez GeneID 7430;
Swissprot P15311
WB Predicted band size 70kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P).
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000

Western blot analysis of extracts from K562 cells, using Ezrin (Ab-478) antibody P41698.
Western blot analysis of extracts from COS7 cells (Lane 2), using Ezrin (Ab-478) antiobdy P41698. The lane on the left is treated with synthesized peptide.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。