Rabbit Polyclonal Antibody to FANCG

包装: 1G|100G|500G|1KG|100KG

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别名:Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.

Description

The Fanconi anemia complementation group (FANC) currently
includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2,
FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM
and FANCN (also called PALB2). The previously defined group FANCH
is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability,
hypersensitivity to DNA crosslinking agents, increased chromosomal
breakage, and defective DNA repair. The members of the Fanconi
anemia complementation group do not share sequence similarity; they
are related by their assembly into a common nuclear protein
complex. This gene encodes the protein for complementation group G.

Specification
Aliases	Fanconi anemia group G protein, Protein FACG, DNA repair protein XRCC9, FANCG, XRCC9
Entrez GeneID	2189
Swissprot	O15287
WB Predicted band size	68.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This FANCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-568 amino acids from the C-terminal region of human FANCG.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	FANCG Antibody (C-term) (Cat. #P31511) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the FANCG antibody detected the FANCG protein (arrow).
	FANCG Antibody (C-term) (P31511)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FANCG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.