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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to FANCL(C-term)

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别名:E3 ubiquitin-protein ligase FANCL, 632-, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, FANCL, PHF9
应用:WB
反应种属:Human
规格:50μl/100μl

Description
The Fanconi anemia complementation group (FANC) currently
includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2,
FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM
and FANCN (also called PALB2). The previously defined group FANCH
is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability,
hypersensitivity to DNA crosslinking agents, increased chromosomal
breakage, and defective DNA repair. The members of the Fanconi
anemia complementation group do not share sequence similarity; they
are related by their assembly into a common nuclear protein
complex. This gene encodes the protein for complementation group L.
Alternative splicing results in two transcript variants encoding
different isoforms.
Specification
Aliases E3 ubiquitin-protein ligase FANCL, 632-, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, FANCL, PHF9
Entrez GeneID 55120
Swissprot Q9NW38
WB Predicted band size 42.9kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

FANCL Antibody (C-term) (Cat. #P32241) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the FANCL antibody detected the FANCL protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。