Rabbit Polyclonal Antibody to FBXO21

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:F-box only protein 21, FBXO21, FBX21, KIAA0875
应用:WB,IHC
反应种属:Mouse
规格：50μl/100μl

Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.

Description

This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),
which function in phosphorylation-dependent ubiquitination. The
F-box proteins are divided into 3 classes: Fbws containing WD-40
domains, Fbls containing leucine-rich repeats, and Fbxs containing
either different protein-protein interaction modules or no
recognizable motifs. The protein encoded by this gene belongs to
the Fbxs class. Alternative splicing of this gene generates 2
transcript variants.

Specification
Aliases	F-box only protein 21, FBXO21, FBX21, KIAA0875
Entrez GeneID	23014
Swissprot	O94952
WB Predicted band size	72.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This FBXO21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-501 amino acids from the C-terminal region of human FBXO21.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	FBXO21 Antibody (C-term) (Cat. #P30947) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the FBXO21 antibody detected the FBXO21 protein (arrow).
	FBXO21 Antibody (C-term) (Cat. #P30947)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBXO21 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.