Rabbit Polyclonal Antibody to FBXO24

包装: 1G|100G|500G|1KG|100KG

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别名:F-box only protein 24, FBXO24, FBX24
应用:WB,IHC,FCM
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Description

This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbxs class. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].

Specification
Aliases	F-box only protein 24, FBXO24, FBX24
Entrez GeneID	26261
Swissprot	O75426
WB Predicted band size	64.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This FBXO24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human FBXO24.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	FBXO24 Antibody (Center) (Cat. #P30891) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FBXO24 antibody detected the FBXO24 protein (arrow).
	FBXO24 Antibody (Center) (Cat. #P30891) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FBXO24 antibody detected the FBXO24 protein (arrow).
	FBXO24 Antibody (Center) (Cat. #P30891) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	FBXO24 antibody (Center) (Cat. #P30891) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXO24 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.