Rabbit Polyclonal Antibody to FGF18

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别名:FGF18; Fibroblast growth factor 18; FGF-18; zFGF5
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small inTine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small inTine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Specification
Aliases	FGF18; Fibroblast growth factor 18; FGF-18; zFGF5
Entrez GeneID	8817
Swissprot	O76093
WB Predicted band size	Calculated MW: 24 kDa; Observed MW: 28 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF18. AA range:158-207
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ELISA	1/10000

	Western blot analysis of FGF18 in SW480, SKOV-3, BT474, mouse heart lysates using FGF18 antibody.
	Immunohistochemistry analysis of paraffin-embedded rat lung using FGF18 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
	Immunohistochemistry analysis of paraffin-embedded mouse lung using FGF18 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.