别名:Fibroblast growth factor 23; FGF-23; Tumor-derived hypophosphatemia-inducing factor; HYPF;应用:WB,ICC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL By similarity. Acts directly on the parathyroid to decrease PTH secretion By similarity. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.Yamashita T., Biochem. Biophys. Res. Commun. 277:494-498(2000).White K.E., Nat. Genet. 26:345-348(2000).Shimada T., Proc. Natl. Acad. Sci. U.S.A. 98:6500-6505(2001). |
Specification | |
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Aliases | Fibroblast growth factor 23; FGF-23; Tumor-derived hypophosphatemia-inducing factor; HYPF; |
Entrez GeneID | 8074; |
Swissprot | Q9GZV9 |
WB Predicted band size | 27kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human FGF23. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
ICC | 1/100-1/500 |
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Western blot analysis of extracts from JK cells, using FGF23 antiobdy P42198. |
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Immunofluorescence analysis of HuvEc cells, using FGF23 antibody P42198. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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