Rabbit Polyclonal Antibody to FGF7

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别名:Fibroblast growth factor 7 , KGF, HBGF-7
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Specification
Aliases	Fibroblast growth factor 7 , KGF, HBGF-7
Entrez GeneID	2252;
Swissprot	P21781
WB Predicted band size	23kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide corresponding to a region derived from 179-182 amino acids of Human Fibroblast growth factor 7
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/1000-1/3000
IHC	1/50-1/200
ELISA	1:500-1:5000

	Gel: 10%SDS-PAGELane1: Human gastric cancer tissue lysateLane2: Human esophagus cancer tissue lysateLysate: 40ugPrimary antibody: 1/1250 dilutionSecondary antibody: Donkey anti Rabbit IgG – H&L (HRP) at 1/5000 dilutionExposure time: 1 second
	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 31162 (FGF7 Antibody) at dilution 1/15, on the right is treated with the synthetic peptide.