中文 
别名:BFGFR; CEK; FLG; CD331; FLT2应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990)Dionne C.A., EMBO J. 9:2685-2692(1990)Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990) |
| Specification | |
|---|---|
| Aliases | BFGFR; CEK; FLG; CD331; FLT2 |
| Entrez GeneID | 2260; |
| Swissprot | P11362 |
| WB Predicted band size | 91kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 463/466(S-E-Y(p)-E-L) derived from Human FGFR1/2. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody P40473.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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