别名:SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr应用:WB,IHC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. |
Specification | |
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Aliases | SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr |
Entrez GeneID | 2268; |
Swissprot | P09769 |
WB Predicted band size | 59kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human FGR |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
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Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: Raw264.7 and raji cell Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds |
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P43412 at dilution 1/20. |
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Immunohistochemical analysis of paraffin-embedded Human brain tissue using P43412 at dilution 1/20. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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