Rabbit Polyclonal Antibody to FHL2

包装: 1G|100G|500G|1KG|100KG

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别名:DRAL; AAG11; FHL-2; SLIM3; SLIM-3
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Description

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specification
Aliases	DRAL; AAG11; FHL-2; SLIM3; SLIM-3
Swissprot	Q14192
WB Predicted band size	32 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human FHL2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/1000-1/5000
IHC	1/100-1/300
ELISA	1/2000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: P08335(FHL2 Antibody) at dilution 1/2400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P08335(FHL2 Antibody) at dilution 1/50. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08335(FHL2 Antibody) at dilution 1/50. (Original magnification: ×200)