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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to FMN2

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别名:Formin-2;
应用:IHC
反应种属:Human,Mouse
规格:50μl/100μl

Description
Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis By similarity. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.toki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Leader B., ” Mech. Dev. 93:221-231(2000).Matsuoka S., Science 316:1160-1166(2007).
Specification
Aliases Formin-2;
Entrez GeneID 56776;
Swissprot Q9NZ56
WB Predicted band size 180kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human FMN2.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
IHC 1/50-1/100

Immunohistochemistry analysis of paraffin-embedded human brain tissue using FMN2 antibody P42407.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。