Rabbit Polyclonal Antibody to FOXD3

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别名:Forkhead box protein D3; HNF3/FH transcription factor genesis; FOXD3;
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Binds to the consensus sequence 5′-A[AT]T[AG]TTTGTTT-3′ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.Gregory S.G., Nature 441:315-321(2006).Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.

Description

Binds to the consensus sequence 5′-A[AT]T[AG]TTTGTTT-3′ and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.Gregory S.G., Nature 441:315-321(2006).Guo Y., Proc. Natl. Acad. Sci. U.S.A. 99:3663-3667(2002).Ramsey H.C., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.

Specification
Aliases	Forkhead box protein D3; HNF3/FH transcription factor genesis; FOXD3;
Entrez GeneID	27022;
Swissprot	Q9UJU5
WB Predicted band size	48kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human FOXD3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HUVEC cells and 293 cells, using FOXD3 antibody P42136.
	Immunohistochemistry analysis of paraffin-embedded human heart tissue using FOXD3 antibody P42136.