Rabbit Polyclonal Antibody to FREQ (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Description

This gene is a member of the neuronal calcium sensor gene
family, which encode calcium-binding proteins expressed
predominantly in neurons. The protein encoded by this gene
regulates G protein-coupled receptor phosphorylation in a
calcium-dependent manner and can substitute for calmodulin. The
protein is associated with secretory granules and modulates
synaptic transmission and synaptic plasticity. Multiple transcript
variants encoding different isoforms have been found for this gene.

Specification
Aliases	Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ
Entrez GeneID	23413
Swissprot	P62166
WB Predicted band size	21.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This FREQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FREQ.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	FREQ Antibody (N-term) (Cat. #P31496) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FREQ antibody detected the FREQ protein (arrow).
	FREQ Antibody (N-term) (P31496)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FREQ Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.