中文 
别名:SNT-1; SNT2; FGFR signalling adaptor;应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways. Xu H., J. Biol. Chem. 273:17987-17990(1998)Meakin S.O., J. Biol. Chem. 274:9861-9870(1999)Dhalluin C., Mol. Cell 6:921-929(2000) |
| Specification | |
|---|---|
| Aliases | SNT-1; SNT2; FGFR signalling adaptor; |
| Entrez GeneID | 10818; |
| Swissprot | Q8WU20 |
| WB Predicted band size | 65kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2 . |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using FRS2 (Phospho-Tyr436) Antibody P40470. The lane on the left is treated with antigen-specific peptide. |
 |
Immunohistochemical analysis of paraffin-embedded human brain tissue using FRS2 (Phospho-Tyr436) antibody P40470 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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