Rabbit Polyclonal Antibody to FUNDC2

包装: 1G|100G|500G|1KG|100KG

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别名:DC44; HCC3; HCBP6; PD03104
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter’s syndrome. A single copy of X alone leads to Turner’s syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Description

FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter’s syndrome. A single copy of X alone leads to Turner’s syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Specification
Aliases	DC44; HCC3; HCBP6; PD03104
Swissprot	Q9BWH2
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human FUNDC2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/300
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P03030(FUNDC2 Antibody) at dilution 1/60. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P03030(FUNDC2 Antibody) at dilution 1/60. (Original magnification: ×200)