Rabbit Polyclonal Antibody to FUT3

包装: 1G|100G|500G|1KG|100KG

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别名:Galactoside 3(4)-L-fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Lewis FT; Fucosyltransferase 3; FucT-III
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.Kukowska-Latallo J.F., Genes Dev. 4:1288-1303(1990).Cameron H.S., J. Biol. Chem. 270:20112-20122(1995).Rahim I., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

Description

May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.Kukowska-Latallo J.F., Genes Dev. 4:1288-1303(1990).Cameron H.S., J. Biol. Chem. 270:20112-20122(1995).Rahim I., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

Specification
Aliases	Galactoside 3(4)-L-fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Lewis FT; Fucosyltransferase 3; FucT-III
Entrez GeneID	2525;
Swissprot	P21217
WB Predicted band size	42kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human FUT3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from K562 cells and Jurkat cells, using MRPS7 antibody P42411.
	Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using MRPS7 antibody P42411.