别名:Alpha-(1,6)-fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose–glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, FUT8应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified. |
Specification | |
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Aliases | Alpha-(1,6)-fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose–glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, FUT8 |
Entrez GeneID | 2530 |
Swissprot | Q9BYC5 |
WB Predicted band size | 66.5kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Application | |
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WB | 1/1000 |
IHC | 1/100-1/500 |
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All lanes : Anti-FUT8 Antibody (Center) at 1:2000 dilution Lane 1: MDA-MB-231 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Observed band size : 65kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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FUT8 Antibody (Center) (Cat. #P35110) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the FUT8 antibody detected the FUT8 protein (arrow). |
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FUT8 Antibody (Center) (Cat. #P35110)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUT8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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