别名:DKFZp564G072; FLJ95923; Frizzled-1; Fz-1; FZD1; FzE1; hFz1; Wnt receptor应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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Members of the ‘frizzled’ gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B. |
Specification | |
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Aliases | DKFZp564G072; FLJ95923; Frizzled-1; Fz-1; FZD1; FzE1; hFz1; Wnt receptor |
Entrez GeneID | 8321; |
Swissprot | Q9UP38 |
WB Predicted band size | 71kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to residues near the N terminal of human Frizzled family receptor 1 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/200-1/1000 |
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Gel: 8%SDS-PAGE Lysate: 40ug 293T cell Primary antibody: 1/500 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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