Rabbit Polyclonal Antibody to GCF

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别名:C2orf3; GC-rich sequence DNA-binding factor; GCF; TCF-9; Transcription factor 9
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Factor that represses transcription. It binds to the GC-rich sequences (5′-GCGGGGC-3′) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.Kageyama R., Cell 59:815-825(1989).Hillier L.W., Nature 434:724-731(2005).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Description

Factor that represses transcription. It binds to the GC-rich sequences (5′-GCGGGGC-3′) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.Kageyama R., Cell 59:815-825(1989).Hillier L.W., Nature 434:724-731(2005).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Specification
Aliases	C2orf3; GC-rich sequence DNA-binding factor; GCF; TCF-9; Transcription factor 9
Entrez GeneID	6936;
Swissprot	P16383
WB Predicted band size	80kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human GCF.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.