Rabbit Polyclonal Antibody to GCNT2

包装: 1G|100G|500G|1KG|100KG

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别名:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Description

This gene encodes the enzyme responsible for formation of
the blood group I antigen. The i and I antigens are distinguished
by linear and branched poly-N-acetyllactosaminoglycans,
respectively. The encoded protein is the I-branching enzyme, a
beta-1,6-N-acetylglucosaminyltransferase responsible for the
conversion of fetal i antigen to adult I antigen in erythrocytes
during embryonic development. Mutations in this gene have been
associated with adult i blood group phenotype. Alternatively
spliced transcript variants encoding different isoforms have been
described.

Specification
Aliases	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Swissprot	Q06430
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-391 amino acids from the C-terminal region of human GCNT2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	GCNT2 Antibody (C-term) (Cat. #P30743) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GCNT2 antibody detected the GCNT2 protein (arrow).
	GCNT2 antibody (C-term) (Cat. #P30743) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GCNT2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.