别名:GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
| Specification | |
|---|---|
| Aliases | GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1 |
| Swissprot | P56159 |
| WB Predicted band size | 51 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human GFRA1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/1000-1/3000 |
| ELISA | 1/1000-1/10000 |
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Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: 293T cells, Primary antibody: P10911(GFRA1 Antibody) at dilution 1/1250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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