Rabbit Polyclonal Antibody to GLCTK

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Glycerate kinase; EC 2.7.1.31; HBeAg-binding protein 4; GLYCTK; HBEBP4
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.Guo J.-H., DNA Seq. 17:1-7(2006).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Ota T., Nat. Genet. 36:40-45(2004).

Description

Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.Guo J.-H., DNA Seq. 17:1-7(2006).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Ota T., Nat. Genet. 36:40-45(2004).

Specification
Aliases	Glycerate kinase; EC 2.7.1.31; HBeAg-binding protein 4; GLYCTK; HBEBP4
Entrez GeneID	132158;
Swissprot	Q8IVS8
WB Predicted band size	60kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from internal of human GLCTK.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100
ICC	1/100-1/500

	Western blot analysis of extracts from 3T3 cells, using GLCTK antibody P42038.
	Immunofluorescence analysis of A549 cells, using GLCTK antibody P42038.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue using GLCTK antibody P42038.