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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to GLRB (N-term)

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别名:Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes the beta subunit of the glycine
receptor, which is a pentamer composed of alpha and beta subunits.
The receptor functions as a neurotransmitter-gated ion channel,
which produces hyperpolarization via increased chloride conductance
due to the binding of glycine to the receptor. Mutations in this
gene cause startle disease, also known as hereditary hyperekplexia
or congenital stiff-person syndrome, a disease characterized by
muscular rigidity. Alternative splicing results in multiple
transcript variants.
Specification
Aliases Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Entrez GeneID 2743
Swissprot P48167
WB Predicted band size 56.1kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody (N-term)(Cat. #P31559). P31559 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。