Rabbit Polyclonal Antibody to GluR4

包装: 1G|100G|500G|1KG|100KG

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别名:Metabotropic glutamate receptor 4; mGluR4; GPRC1D; MGLUR4; GRM4
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 – 6313.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 – 224.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 – 224.Peyman Golshani, PNAS, Mar 2001; 98: 4172.

Description

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 – 6313.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 – 224.Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 – 224.Peyman Golshani, PNAS, Mar 2001; 98: 4172.

Specification
Aliases	Metabotropic glutamate receptor 4; mGluR4; GPRC1D; MGLUR4; GRM4
Entrez GeneID	2914;
Swissprot	Q14833
WB Predicted band size	100kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from human GluR4.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from 293 cells, untreated or treated with Forskolin (40nM, 30mins), using GluR4 antibody P41805.
	Western blot analysis of extracts from JK cells (Lane 2), using mGluR4 antiobdy P41805. The lane on the left is treated with synthesized peptide.
	Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR4 antibody P41805.