Rabbit Polyclonal Antibody to GluR5

包装: 1G|100G|500G|1KG|100KG

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别名:EAA3; EEA3; GLR5; GLUTAMATE RECEPTOR 5; excitatory amino acid receptor 3
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.Ana V. Paternain, J. Neurosci., Jan 2000; 20: 196.Zhao Ren, J. Biol. Chem., Dec 2003; 278: 52700 – 52709.MICHAEL A. ROGAWSKI, Ann. N.Y. Acad. Sci., Apr 2003; 985: 150.Yoshinori Sahara, J. Neurosci., Sep 1997; 17: 6611.

Description

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.Ana V. Paternain, J. Neurosci., Jan 2000; 20: 196.Zhao Ren, J. Biol. Chem., Dec 2003; 278: 52700 – 52709.MICHAEL A. ROGAWSKI, Ann. N.Y. Acad. Sci., Apr 2003; 985: 150.Yoshinori Sahara, J. Neurosci., Sep 1997; 17: 6611.

Specification
Aliases	EAA3; EEA3; GLR5; GLUTAMATE RECEPTOR 5; excitatory amino acid receptor 3
Entrez GeneID	2897;
Swissprot	P39086
WB Predicted band size	100kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from human GluR5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from mouse brain, using GluR5 antibody P41806.
	Western blot analysis of extracts from HepG2 cells (Lane 2), using GluR5 antiobdy P41806. The lane on the left is treated with synthesized peptide.
	Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR5 antibody P41806.