Rabbit Polyclonal Antibody to GluR6

包装: 1G|100G|500G|1KG|100KG

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别名:EAA4; GLR6; MGC74427; bA487F5.1 (glutamate receptor; ionotropic
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.Inga Everts, J. Neurosci., Feb 1999; 19: 916.Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 – 40173.Sheng Yan, J. Neurosci., Jan 2004; 24: 679.Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 – 17445.

Description

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.Inga Everts, J. Neurosci., Feb 1999; 19: 916.Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 – 40173.Sheng Yan, J. Neurosci., Jan 2004; 24: 679.Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 – 17445.

Specification
Aliases	EAA4; GLR6; MGC74427; bA487F5.1 (glutamate receptor; ionotropic
Entrez GeneID	2916;
Swissprot	O15303
WB Predicted band size	100kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from human GluR6.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from mouse brain, using GluR6 antibody P41807.
	Western blot analysis of extracts from HepG2 cells (Lane 2), using mGluR6 antiobdy P41807. The lane on the left is treated with synthesized peptide.
	Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR6 antibody P41807.