Rabbit Polyclonal Antibody to GluR8

包装: 1G|100G|500G|1KG|100KG

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别名:GPRC1H; MGLUR8; mGlu8; GLUTAMATE RECEPTOR; METABOTROPIC
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 – 848.RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 – 1339.Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 – 9808.V. Bruno, J. Neurosci., Sep 2000; 20: 6413.

Description

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 – 848.RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 – 1339.Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 – 9808.V. Bruno, J. Neurosci., Sep 2000; 20: 6413.

Specification
Aliases	GPRC1H; MGLUR8; mGlu8; GLUTAMATE RECEPTOR; METABOTROPIC
Entrez GeneID	2918;
Swissprot	O00222
WB Predicted band size	100kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from human GluR8.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from mouse brain, using GluR8 antibody P41809.
	Western blot analysis of extracts from k562 cells (Lane 2), using mGluR8 antiobdy P41809. The lane on the left is treated with synthesized peptide.
	Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR8 antibody P41809.