中文 
别名:Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.Lucka L., FEBS Lett. 454:341-344(1999).Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. |
| Specification | |
|---|---|
| Aliases | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase; UDP-GlcNAc-2-epimerase; Uridine diphosphate-N-acetylglucosamine-2-epimeraseN-acetylmannosamine kinase |
| Entrez GeneID | 10020; |
| Swissprot | Q9Y223 |
| WB Predicted band size | 80kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from C-terminal of human GNE. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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Western blot analysis of extracts from NIH/3T3 cells, using GNE antibody P42699. |
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Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using GNE antibody P42699. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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