Rabbit Polyclonal Antibody to GP6

包装: 1G|100G|500G|1KG|100KG

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别名:GPIV; GPVI; BDPLT11
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Description

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specification
Aliases	GPIV; GPVI; BDPLT11
Swissprot	Q9HCN6
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human GP6
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/40-1/200
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13469(GP6 Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13469(GP6 Antibody) at dilution 1/40. (Original magnification: ×200)