库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to GPC3

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别名:Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3, GPC3, OCI5
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Cell surface heparan sulfate proteoglycans are composed of
a membrane-associated protein core substituted with a variable
number of heparan sulfate chains. Members of the glypican-related
integral membrane proteoglycan family (GRIPS) contain a core
protein anchored to the cytoplasmic membrane via a glycosyl
phosphatidylinositol linkage. These proteins may play a role in the
control of cell division and growth regulation. The protein encoded
by this gene can bind to and inhibit the dipeptidyl peptidase
activity of CD26, and it can induce apoptosis in certain cell
types. Deletion mutations in this gene are associated with
Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia
syndrome. Alternative splicing results in multiple transcript
variants.
Specification
Aliases Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3, GPC3, OCI5
Entrez GeneID 2719
Swissprot P51654
WB Predicted band size 65.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human GPC3.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

GPC3 Antibody (C-term) (Cat. #P31538) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GPC3 antibody detected the GPC3 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。