Rabbit Polyclonal Antibody to GPNMB

包装: 1G|100G|500G|1KG|100KG

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别名:Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
应用:WB
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene is a type I transmembrane
glycoprotein which shows homology to the pMEL17 precursor, a
melanocyte-specific protein. GPNMB shows expression in the lowly
metastatic human melanoma cell lines and xenografts but does not
show expression in the highly metastatic cell lines. GPNMB may be
involved in growth delay and reduction of metastatic potential. Two
transcript variants encoding different isoforms have been found for
this gene.

Specification
Aliases	Transmembrane glycoprotein NMB, Transmembrane glycoprotein HGFIN, GPNMB, HGFIN, NMB
Entrez GeneID	10457
Swissprot	Q14956
WB Predicted band size	63.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This GPNMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human GPNMB.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.