Rabbit Polyclonal Antibody to GPR3

包装: 1G|100G|500G|1KG|100KG

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别名:G protein-coupled receptor 3, ACCA
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer’s disease.

Description

This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer’s disease.

Specification
Aliases	G protein-coupled receptor 3, ACCA
WB Predicted band size	35kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide corresponding to a region derived from 318-330 amino acids of Human G protein-coupled receptor 3
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1:1000-1:5000

	Gel: 10%SDS-PAGE Lysate: 40ug Human brain malignant glioma tissue lysate Primary antibody: 1/1100 dilution Secondary antibody: Goat anti Rabbit IgG – H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes
	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31211 (GPR3 Antibody) at dilution 1/55, on the right is treated with the synthetic peptide.