Rabbit Polyclonal Antibody to GRB14

包装: 1G|100G|500G|1KG|100KG

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别名:
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

Description

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

Specification
Swissprot	Q14449
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human GRB14
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/25-1/100
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07325(GRB14 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07325(GRB14 Antibody) at dilution 1/20. (Original magnification: ×200)