别名:GRIN2B; NMDE2; NME2; NR2B; NR3应用:WB
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.Adams S.L., Biochim. Biophys. Acta 1260:105-108(1995)Hess S.D., J. Pharmacol. Exp. Ther. 278:808-816(1996)Mandich P., Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases |
Specification | |
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Aliases | GRIN2B; NMDE2; NME2; NR2B; NR3 |
Entrez GeneID | 2904; |
Swissprot | Q13224 |
WB Predicted band size | 170kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of Serine 1303(Q-H-S(p)-Y-D) derived from Human GRIN2B. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of extracts from Mouse brain cells using GRIN2B (Phospho-Ser1303) Antibody P40520.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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